Featured Books


Differential Diagnosis Of Chronic Hepatitis

Diagnosis Banding Hepatitis Kronik

Diagnosis Screening Tests Confirmatory Tests (Serum or Liver) Comments
Chronic hepatitis B HBsAg HBV DNA, HBeAg, or
HBcAg in liver

Chronic hepatitis C Anti-HCV HCV RNA (using PCR) Immunoblot for anti-HCV can be used to confirm antibody reactivity
Chronic hepatitis D Anti-HDV HDV RNA or HDV antigen in the liver
Autoimmune hepatitis ANA (anti-LKM1) Exclusion of other causes and patterns of clinical disease Suggested by raised IgG levels and by response to corticosteroid therapy
Drug-induced liver disease History Rechallenge, if necessary, is considered safe Medications most suspected include isoniazid, NSAIDs, methyldopa, nitrofurantoin
Wilson's disease Ceruloplasmin Urine and hepatic copper concentration Suggested by hemolysis or severe chronic hepatitis in a child or adolescent
Cryptogenic Exclusion of other causes Major differential is with autoimmune hepatitis and drug-induced liver disease

  • ANA = antinuclear antibody
  • anti-LKM1 = liver-kidney microsomal 1 antibody
  • HBcAg = hepatitis B core antigen
  • HBeAg = hepatitis B e antigen
  • HBsAg = hepatitis B surface antigen
  • HBV = hepatitis B virus 
  • HCV = hepatitis C virus
  • HDV = hepatitis D virus
  • IgG = immunoglobulin G 
  • NSAIDs = nonsteroidal anti-inflammatory drugs 

Cecil Medicine 23rd Edition (Saunders) 2008

Download table

Copyright 2010 ReadingFirst | Digital Bookstore - All Rights Reserved.
Designed by Web2feel.com | Bloggerized by Lasantha - Premiumbloggertemplates.com | Affordable HTML Templates from Herotemplates.com.